OBSERVATION ON LECTIN RECEPTORS IN GLANDS OF INTESTINAL METAPLASIA OF GASTRIC MUCOSA
- VernacularTitle:胃粘膜肠上皮化生腺体的凝集素受体观察
- Author:
Jianhua TAO
;
Yanyun ZHU
;
Zhenyan LIU
- Publication Type:Journal Article
- Keywords:
Lectin;
Histochemistry;
Intestinal metaplasia;
Dysplasia;
Gastric cancer
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
4 kinds of lectin receptors (PHA, DBA, PNA, ConA) in the tissues of a variety of lesions of the gastric mucosa are studied with the histochemical method (ABC technique) in 87 cases. The results are follows: the positive rates of 4 kinds of lectin-binding, the distribution of lectin receptors, the intensity of positiveness and the stained patterns are correlated to the histologic types and the grades of various mucosal lesions. The intensity of positive reaction of PHA, PNA and DBA shows a progressive rising, while that of ConA appears a gradual declining tendency with the change from normal gastric mucosa to intestinal metaplasia and cancer. The stained patterns of lectin are: type I is the main pattern for ConA, type I for PNA and type III for PHA and DBA .