Changes of N-acetyl-?-glucosaminidase in Sera of Patients with Hepatoma and Other Diseases
- VernacularTitle:肝癌和其他肝疾病患者血清中N-乙酰-?氨基葡萄糖苷酶活性变化
- Author:
Shimin ZHANG
;
Mengchao WU
;
Han CHEN
- Publication Type:Journal Article
- Keywords:
liver neoplasms;
liver diseases;
acetyl glucosaminidase;
spectrophotometry;
serodiagnosis
- From:
Academic Journal of Second Military Medical University
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Activities of N-acetyl-?-glucosaminidase (NAG) in sera of normal subjects and patients with hepatocellular carcinoma (HCC) and other diseases were microquantitatively determined by spectrophotometry. The results showed that after the reaction for 4 h, activity of serum NAG in patients with HCC (397.10 ? 174.97 nmol/ml) was obviously higher than that in normal subjects (280.00 ? 63.83 nmol/ml). The elevation of serum NAG in HCC patients had no relationship with their serum a-fetoprotein. However, the increase of serum NAG activity in some patients with benign liver diseases was always accompanied by the abnormality in their liver functions. It is suggested that serum NAG has some referable values in the diagnosis of HCC.
