Hepatotoxicity of Cyclosponne in Renal Allograft Recipients
- VernacularTitle:肾移植中环孢素的肝脏毒性作用
- Author:
Guanghui LI
;
Zhilian MIN
;
Changmin HE
;
Youhua ZHU
;
Jun QI
;
Gang MENG
- Publication Type:Journal Article
- Keywords:
cyclosporine A;
hepatotoxicity;
renal allografts;
incidence
- From:
Academic Journal of Second Military Medical University
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Hepatotoxicity of cyclosporine A was investigated in 366 patients who received renal allografts, of whom 94 (25.68%) presented hepatotoxicity and 13 (3.55%) died. Hepatotoxicity appeared between 7 and 84 d, and lasted for 5 to 96 d. Our study suggested that cyclosporine A is not suitable for older patients with positive HBsAg and liver disfunction.
