Establishment of a mouse model of transplantable mammary spindle cell carcinoma SCC891
- VernacularTitle:小鼠可移植性乳腺梭形细胞癌模型(SCC891)的研究
- Author:
Hong WEI
;
Xuyou QU
;
Lanhui LUO
- Publication Type:Journal Article
- Keywords:
breast neoplasms;
mice;
spindle cell carcinoma;
disease models ,animal
- From:Journal of Third Military Medical University
1988;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
After screening,the authors established a mouse model of pathomorphologically special,transplantable mammary spindle cell carcinoma SCC 891 in BALB/c mice.After 48 passages in 2.5 years,the growth of the tumor strain became stable with a 100% transplantibility.Its growth was quite active without observable spontaneous regression.The mean life span of the host mouse was 35.2?7.3 days.BALB/c mice of both sexes and of any age were susceptable to the carcinoma,and the carcinoma was sensitive to various anticancer drugs.
