Glycated ?-Lipoprotein: An Indicator of Diabedc Vascular Complications
- VernacularTitle:?-脂蛋白非酶糖化水平作为糖尿病血管并发症的指标
- Author:
Yong GE
;
Jiaqing ZHANG
;
Yunping ZHOU
- Publication Type:Journal Article
- Keywords:
diabtes mellitus;
glycosylation;
diabetic angiopathies
- From:
Academic Journal of Second Military Medical University
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
We described a simple method for determining glycated lipoproteins (glc Lps) in serum by agarose gel film electrophoresis, and color development with nitroblue tetrazolium. The resulting blue bands on the film were measured densitometrically at 545 nm to quantify ?-, pre-?-, and ?-glc Lps. The concentration of gfc ?-Lp in serum from diabetics was 2,2-fold higher than that in normal individuals. Diabetic patients with vascular complications had higher concentrations of glc ?-Lp than did patients without vascular complication. The concentration of glc ?-Lp (glc LDL) in serum may be a useful diagnostic indicator of diabetic vascular complications and their severity.
