Effects of burn injury and eschar lipids on hepatic mitochondrial content of fatty acid in rats
- VernacularTitle:烧伤及烧伤焦痂脂类对大鼠肝线粒体脂肪酸含量的影响
- Author:
Ye XIONG
;
Zongrong CHEN
- Publication Type:Journal Article
- Keywords:
burns;
lipids;
mitochondrion;
fatty acids;
chromatography;
gas
- From:Journal of Third Military Medical University
1983;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The fatty acid content of liver mitochondria was quantitatively determinde with gas chromatography in rats after they were inflicted with 15% TBSA full thickness burns or after the liver mitochondria were incubated with lipids extracted from eschar tissue(D1)or from normal skin of rats(D'1).It was found that after burn injury,the content of unsaturated fatty acid of liver mitochondria decreased and that of saturated fatty acid increased significantly.Both Dl and D'l decreased the content of unsaturated fatty acid and the decrease would be more significant when the concentration of eschar lipids or skin lipids was increased.D1 reduced the unsaturated fatty acid content more significant than D'1 when the two were in same concentration.The possible mechanism of the decrease of unsaturated fatty acid in the liver mitochondria induced with burn injury,eschar lipids or normal skin lipids was discussed briefly.
