A sduty on transplantation of embryonic spinal cord and favorable factors for its acceptance after acute spinal cord injury in rats
- VernacularTitle:急性脊髓损伤后胎鼠脊髓的脊髓内移植及其影响因素
- Author:
Bingcang LI
;
Yamin WU
;
Mei LIU
- Publication Type:Journal Article
- Keywords:
spinal cord injuries;
spinal cord/TR
- From:Journal of Third Military Medical University
1983;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Transplantation of embryonic spinal cord was performed with microsurgical technique in rats after they were inflicted with acute spinal cord injury.Then the favorable factors affecting the acceptance of the transplanted cord were investigated with morphological technique.It was found that among the gestation ages from EH to E20,the spinal cord taken from the rats with the gestation age of E14 showed the highest survival rate of 70.83%.None of the transplants taken from the rats with the gestation age older than E14 survived.The connective tissue attached to transplants severely interfered with their acceptance and growth.The severity of the pathological manifestations of the injured spinal cord exerted unfavorable influence on the survival and growth of the transplants too.It is believed that in order to assure the success of the transplantation,besides the attention on the technical performance of the surgery,it is essential to determine the differentiation state of the embryonic spinal cord to be transplanted.
