Effects of load-dose Amrinone on left ventricular function in heart failure patients evaluated by echocardiography
- VernacularTitle:超声心动图评价负荷量国产氨吡酮对心力衰竭病人左心功能的影响
- Author:
Dongye LI
;
Meiling LIAN
;
Lanfen WU
- Publication Type:Journal Article
- Keywords:
Amrinone;
Left ventricular function;
Congestive heart failure;
Echocardiography
- From:
Chinese Pharmacological Bulletin
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of Amrinone (AMR)on left ventricular function in 30 cases of congestive heart failure patients was assessed by M-mode and pulsed Doppler echocardiography. AMR improves the systolic and diastolic function of left ventricle during and after 10 min (AMR lmg ? kg-1, infusion ). The mean stroke volume increased 20% and 18% ; cardiac output increased 23% , 19% ; cardiac index increased 23% and 23% ; ejection fraction increased 32% , 30%; mVcf increased 50% and 48% ; filling velocity in early diastole increased 30% and 21 %; respectively. There were no significant differently between during and after AMR infusion, but there were signifcantly difference a-mong before, during and after AMR infusion. The heart rate changed slightly without statistic significance. The results suggest that AMR could improve the systolic and diastolic function of left ventricle in congestive heart failure patients.
