A STUDY OF PGE AND PGF_(2a) RELEASING CAPACITY OF ALVEOLAR MACRO PHAGES IN ASTHMATICS
- VernacularTitle:哮喘患者肺泡巨噬细胞释放前列腺素E、F_(2?)的实验研究
- Author:
Diantao NI
;
Bin SUN
- Publication Type:Journal Article
- Keywords:
Asthma;
Prostaglandin E;
Prostaglandin F2a;
Alveolar macrophagcs
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Bronchoalveolar lavage (BAL) was performed in healthy subjects (n = 12) and patients with bronchial asthma (n = ll). Between two groups there were no significant differences in total cells and percentage of alveolar macrophages (AM), lymphocytes, ncutrophils, cosinophils in BAL fluids. When AM were cultured in vitro and stimulated with dermatophagoides farinae(DPF) antigen, the quantity of PGE released by AM was significantly increased in asthmatics. When asthmatics' AM were sensitized with specific IgE positive serum and stimulated with DPF, they released more PGE, PGF2a than that when specific IgE negative serum was used (P
