Correlation between the Number of AgNOR and the Grading and Prognosis of Bladder Tumor
- VernacularTitle:核仁组成区嗜银蛋白定量和膀胱肿瘤分级与预后的关系
- Author:
Dingwei YE
;
Jiafu ZHENG
;
Songxi QIAN
;
Yongjiang MA
- Publication Type:Journal Article
- Keywords:
bladder neoplasms;
nucleolus organizer region;
prognosis;
immunohistochemistry
- From:
Academic Journal of Second Military Medical University
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The numbers of nucleolar organizer region (AgNOR) were counted by one-step silver colloid technique in 6 cases of normal bladder tissue, 9 chronic cystitis and 56 transitional cell carcinoma of bladder. The results revealed that the mean number of AgNOR per nucleus was not statistically different between normal bladder tissue and chronic cystitis while a significant difference was observed between normal, or inflammatory tissue and malignant tissue or between various grades of bladder tumor. The results also indicated that the mean number of AgNOR per nucleus was closely related to the prognosis of bladder tumor. So it is suggested that the AgNOR counting with silver stain technique may play a role in the differentiation of benign and malignant lesions and in the grading and prognosis of bladder tumors.
