Effect of Paraventricular Nudetis of Hypothalamus on Pain Regulation in Rats
- VernacularTitle:下丘脑室旁核对痛觉调制的影响
- Author:
Jun YANG
;
Chaoyou SONG
;
Baocheng LIN
;
Henian ZHU
- Publication Type:Journal Article
- Keywords:
paraventricular nucleus of hypothalamus;
pain regulation;
pain threshold;
rats
- From:
Academic Journal of Second Military Medical University
1982;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Methods including stimulation, cauterization, of nuclei and measurement of pain threshold were used to clarify the role of paraventricular nucleus of hypothalamus (PVH) in pain regulation. Results showed that electrical or L-glutamate sodium stimulation of PVH could elevate the pain threshold in the rat dose-dependently, electrical cauterization of PVH could reduce the pain threshold; and removal of the pituitary gland could not influence the effect of L-glutamate sodium on pain threshold. These results suggest that PVH may play an important role in pain regulation.
