Effects of Bile Adds on the Proteins, Enzyme Activities and Ion Permeability of Human Erythrocyte Membrane
- VernacularTitle:胆汁酸对人红细胞膜蛋白质、酶活力和离子通透性的影响
- Author:
Chenhao FAN
;
Weihua FEN
;
Jianxin LI
;
Yaomei WEI
- Publication Type:Journal Article
- Keywords:
bile adds;
erythrocyte membrane;
membrane protein;
enzyme activities;
cell membrane permeability
- From:
Academic Journal of Second Military Medical University
1982;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Fresh healthy human erythrocytes were treated by four kinds of bile acid solutions (DC, GDC, C, and GC) at physiological and pathological concentrations of human plasma, and the membrane proteins, enzyme activities and permeability of cations were observed. The results showed that some components of the membrane cytoskeleton proteins disappeared, the activities of total ATPase and Gr-ATPase were distinctly increased with the increasing of bile acid concentrations, the activity of the membrane acetylcholinesterase was decreased with the increasing bile acid concentrations, the permeability of cations was increased with the increasing bile acid concentrations. The effect of the dihydroxy bile acids more stronger than that of the trihydroxy bile acids.
