Relationship between the state of oxidation-reduction and protein degradation in the scalded soleus muscle of rats
- VernacularTitle:烫伤大鼠比目鱼肌氧化还原状态变化与蛋白质分解代谢的关系
- Author:
Yuancheng WANG
;
Yanlin DONG
- Publication Type:Journal Article
- Keywords:
reduction-oxidation;
protein/ME;
muscle;
burns;
rats
- From:Journal of Third Military Medical University
1984;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
One hind leg(7 %TBSA)of the rat was scalded and the changes of the reduction-oxidation state and protein degradation in the soleus muscle were observed 72 hours postinjury both in vitro and in vivo.It was found that the lactate/pyruvate (L/P) and malate/pyruvate(M/P)ratios of the soleus muscle were significantly lower and the protein degradation rate much higher in the scalded leg than in the unscalded legs and the control.After the addition of insulin to the medium significant elevation of L/P and M/P ratios and reduction of the protein degradation rate in the soleus muscle could be observed.There findings suggest that there is a good correlation between the changes of the reduction-oxidation state and the protein degradation rate in the cytosol of the soleus muscle after scalding in the rat.
