EFFECTS OF TR1TERYGIUM WILFORDII ON THE PRODUCTION OF INTERLEUKIN 2 IN SPLEEN CELL FROM MIC WITH NEPHROTOXIC SERUM NEPHRITIS
- VernacularTitle:雷公藤对肾毒血清性肾炎小鼠白细胞介素-2产生的作用
- Author:
Hongjun LIAO
;
Xiangmei CHEN
;
Qingli CHENG
;
Leishi LI
- Publication Type:Journal Article
- Keywords:
Triterygium Wiifordii;
Interleukin 2;
Nephrotoxic serum nephritis
- From:
Medical Journal of Chinese People's Liberation Army
1983;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Interleukin 2 (IL-2) activity in spleen lymphocyte and anti-Rabbit IgG antibody from mice with nephrotoxic serum nephritis were examined to investigate immunosuppressive effect of Triterygium Wilfordii (TW), IL-2 bioactivity and serum anti-Rabbit IgG antibody were significantly higher in the group of nephrotoxic serum nephritis. The administration of TW prevented the overproduction of IL-2 and serum anti-Rabbit IgG antibody, and reduced excretion of urinary protein and renal histologic changes.
