Functional Changes of Pulmonary Surfactant in Rats Suffering from Scald Complicated by Endotoxemia
- VernacularTitle:大鼠烫伤复合内毒素血症肺表面活性物质功能的变化
- Author:
Huiqin SHENG
;
Xiaoqi GONG
;
Jinshan ZHANG
;
Yafei ZHANG
- Publication Type:Journal Article
- Keywords:
pulmonary surfactant;
burns;
endotoxemia;
phospholipids;
disease models, animal;
rats
- From:
Academic Journal of Second Military Medical University
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The functional changes of pulmonary surfactant (PS) in rats of acute lung injury induced by scald companied with endotoxemia were studied The surface properties of the bronch-alveolar lavags fluid (BALF) and the total phospholipids extracted frome it were assessed on a modified Whilhemy film balance. The results showed hat the total phospholipids, phosphatidylcholine, and phosphatidyl glycerol in the BALF were decreased the total proteins in the BALF were increased and the function of PS of the BALF were reduced which may be caused by increased serum proteins in the alveoli and decreased surface activity of phospholipids themselves.
