MACHANISM OF PROTECTIVE EFFECTS AGAINST ENDOTOXIC SHOCK BY THE PANAXAKIOL SAPONIN
- VernacularTitle:人参二醇组皂甙对内毒素性休克保护作用机制的实验研究
- Author:
Yuanyuan LIU
;
Xuejian ZHAO
;
Meide LU
- Publication Type:Journal Article
- Keywords:
Endotoxin;
Shock;
Ginsenoside;
5-HT;
Lipidperoxide;
Noradrenaline
- From:
Chinese Pharmacological Bulletin
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Experimental models were reproduced by injection of crude E. Coli. endotoxin into the abdominal cavity in rats. One handred and twenty-eight Wistr rats were -randomly divided into 3 groups: endotoxic shock ( ESG ) , group pretreated with psnasadiol saponin (ESPG) and control group(CG). It was found that 16h survival rate in ESPG was higher than that in ESG(P