THE CHANGES IN CHEMILUMINESCENCE IN PLASMA AND LUNG LYMPH IN ENDOTOXIN-INDUCED LUNG INJURY
- VernacularTitle:急性肺损伤血浆和肺淋巴液化学发光的改变
- Author:
Yunkui ZHU
;
Bin SUN
;
Jingkai CHEN
- Publication Type:Journal Article
- Keywords:
Lung injury;
Endotoxin;
Chemiluminescence;
Plasma;
Lung lymph;
Lipid peroxides;
Sheep
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The purpose of this study was to determine the role of lipid peroxidation by measuring the induced-chemiluminescence (ICL) of plasma and lung lymph in endotoxin-induced acute lung injury in awake sheep. The ICL of aortic plasma and lung lymph were significantly increased, but the ICL of venous plasma was not significantly increased after endotoxin infusion. The peak level of ICL was increased and its time was delayed after endotoxin. We conclude that lipid peroxidation plays an important role in endotoxin-induced acute lung injury, and ICL of arterial plasma is a sensitive marker in reflecting oxidant damage in lung.
