A study of Kupffer cell phagocytic function during acute obstructive cholangitis in rats
- VernacularTitle:急性胆道感染时枯否细胞吞噬功能变化的实验研究
- Author:
Jianping GONG
;
Bcnli HAN
;
Ding LUO
- Publication Type:Journal Article
- Keywords:
Kupffer cell;
cholangitis;
endotoxins;
fibronectin;
multiple organ failure;
acute disease
- From:Journal of Third Military Medical University
1988;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The phagocytic function of Kupffer cells (KC) during acute obstructive cholangitis was observed in 244 Wistar rats.The rats were killed in the 6th,12th,24th,and 48th hour after operation,and the uptake of colloidal carbon by KC,plasma endotoxin and fibronectin(Fn)were determined and the morphology of KC was observed.It was found that in the rats with acute obstructive cholangitis,the phagocytic function of KC and plasma Fn significantly elevated in the 6th hour and markedly reduced in the 48th hour after operation as compared with those of the control (P
