The study of the relationship between erythrocytic membrane band 3 and acid-base changes in patients with cor pulmonale
- VernacularTitle:肺心病人红细胞膜带3蛋白和酸碱变化的研究
- Author:
Xiaojing YANG
;
Guisheng QIAN
;
Baoling MAO
- Publication Type:Journal Article
- Keywords:
Pulmonary heart disease;
respiratory insufficiency;
erythrocyte membrance;
band 3 protein;
acid-base imbalance
- From:Journal of Third Military Medical University
1988;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The changes of erythrocytic membrane band 3 protein and intraery-throcytic and extrar rythrccytic gases and electrolytes were studied in 69 cases of cor pulmonale and 50 normal subjects.It was found that in the patients of cor pulmonale accompanied with type Ⅱ respiratory failure,the relative low level of erythrocytic membrane band 3 protein and the restriction of HCO-3/Cl-exchange were the factors to aggravate CO2 retention and respiratory acidosis,relative intraerythrocytic alkalosis resulted from the relative increase of intra-erythrocytic HCO-3([HCO-3]),and prompt adminstration of oxygen to cor pulmonale patients with hypoxemia could not only improve extraerythrocytic acid-base imbalance but also increase intraerythcocytic P5O2 and the tissue capacity to store oxygen.
