PROMOTING EFFECT OF PANAXATRIOL GINSENOSIDE ON GENE EXPRESSION OF HUMAN INTERLEUKINE-3
- VernacularTitle:人参三醇皂甙促进人白细胞介素3的基因表达
- Author:
Zhigang TIAN
;
Guizhen YANG
- Publication Type:Journal Article
- Keywords:
Interleukine-3;
mRNA;
Human lymph node cells;
Panaxatriol Ginsenoside;
Gene expression
- From:
Chinese Pharmacological Bulletin
1986;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Promoting effect of panaxatriol ginsenoside ( PTGS ) on inter-leukine-3(IL-3 ) induction of phyto-hemagglutinin ( PHA ) stimulated human lymph node cells was observed. The results showed that PTGS enhanced the IL-3 production on each time of IL-3-induction kinetics, maximally by 30% ( 72h ) . Furthermore, it was observed that IL-3 mRNA from PHA+PTGS-stimulated lymph node cells translated more IL-3 than PHA-stimulated lymph node cells on each time of IL-3 mRNA-induction kinetics, maximally by 40% ( 60h ) , using the methods of wheat germ cell-free in vitro translation system and IL-3 bioassay.
