A STUDY ON SUPPRESSIVE ACTIVITY OF POSTBURN SERUM ON T LYMPHOCYTE PROLIFERATION RESPONSE
- VernacularTitle:烧伤后血清对T淋巴细胞抑制的实验研究
- Author:
Huaping LIANG
;
Yinsheng ZHAO
- Publication Type:Journal Article
- Keywords:
Burn Lymphocyte Interleukin 1 Interleukin 2
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The effect of postburn serum on T lymphocyte proliferation response was studied. The results showed that postburn serum was able to inhibit T lymphocyte transformation. The degree of serum suppression correlated with reduced T lymphocyte transformation after burn. Postburn serum also showed significant suppressive activities upon both interleukin 2 (IL-2) production and interaction betweeen IL-2 and IL-2 receptor (IL-2R), but had no significant effect on interleukin 1 (1L-1) producticn. This result indicated that postburn serum might inhibit IL-2 production and response through certain pathway other than IL-1 production, resulting in impaired T lymphocyte proliferation response.
