Effects of Anaesthesia and Sinoaortic Denervation on the Hypotensive Action of Ketanserin
- VernacularTitle:麻醉和去减压神经对酮舍林降压作用的影响
- Author:
Dingfeng SU
;
Youcai YANG
;
Jinger XIE
- Publication Type:Journal Article
- Keywords:
antihypertensive agents;
anaesthesia;
blood pressure;
ketanserin;
sinoaortic denervation
- From:
Academic Journal of Second Military Medical University
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Effects of anaesthesia and sinoaortic denervation (SAD) on the hypotensive action of , ketanserin were studied in rats. It was found that the dose-effect curves of kelanserin on blood pressure were the same between SAD and sham-operated rats under anaesthesia. However, in concious free ly moving rats, SAD sharpened the dose-effect curves. It is concluded that the lack of hypotensive effect of ketanserin in conscious normotensive animals is due in large part to the integrity of the arterial baroreflex.
