Expression of tumor-associated glycoprotein (TAG-72) in gastric carcinoma and its precancerous lesions
- VernacularTitle:肿瘤相关糖蛋白TAG-72在胃癌及其癌前组织中的表达
- Author:
Dianchun FANG
;
Weiwen LIU
- Publication Type:Journal Article
- Keywords:
stomach neoplasms/DI;
metaplasia;
intestines/PA;
glycoproteins
- From:Journal of Third Military Medical University
1988;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
The expression of tumor-associated glycoprotein (TAG-72) identified by monoclonal antibody B72.3 was investigated in HO resected specimens of gastric carcinoma,36 biopsied specimens of dysplasia,and 303 specimens of intestinal metaplasia(IM).IM was subdivided into complete Type I and incomplete Types Ⅱ and Ⅲ based on whether sulphomucin is present or absent in the mucin secreting columnar cells.The positive rate of TAG-72 in gastric carcinoma was 60.9%,and it was significantly higher in IM specimens with gastric carcinoma than in those with benign gastric lesions (P
