Effects of gunshot wound on lipid peroxidation in plasma and pulmonary tissues and amount of superoxide anions released by PMNs in pigs
- VernacularTitle:猪钢珠弹伤后血浆及肺组织的脂质过氧化与粒细胞活性氧产生量
- Author:
Jihong ZHOU
;
Peifang ZHU
;
Baotong ZHOU
- Publication Type:Journal Article
- Keywords:
wounds, gunshot;
neutrophile;
free radicals;
lipid peroxides;
jnalonyldialdehyde
- From:Journal of Third Military Medical University
1988;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
The amount of superoxide anions released by polymorphonuclear leukocytes (PMNs)and malonyldialdehyde (MDA) level in plasma,lung homoge-nate and bronchoalveolar lavage fluid (BALF) were determined in pigs after they were inflicted with gunshot wounds of steel-ball pellets.It was found that the amount of superoxide anions released spontaneously and after the stimulation of zymosa was increased and reached the peak in the 4th and 8th hour after injury respectively,and then returned to the preinjury level gradually.The changes of plasma MDA level was similar to those of superoxide anions released by PMNs.MDA level of lung homogenate and BALF was also significantly increased in the 24th hour postinjury.In addition,the relationship between PMNs function and lipid peroxidation in the plasma and the lungs was discussed.
