EXPERIMENTAL STUDY ON THE CHANGES IN THE INTESTINAL FLORA IN RABBITS WITH MULTIPLE SYSTEM ORGAN FAILURE
- VernacularTitle:实验性多系统器官功能衰竭家兔肠道菌群改变的动态观察及其意义
- Author:
Yongming YAO
;
Huimin TIAN
;
Yaping WANG
;
Zhiyong SHENG
;
Zhiguo SHI
;
Fusheng LAN
- Publication Type:Journal Article
- Keywords:
Multiple organ failute Intestinal flora Bacterial translocation Endotoxin
- From:
Medical Journal of Chinese People's Liberation Army
1983;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
A new animal model of multiple system organ failure (MSOF) in rabbits is used in this experiment. The purpose of the current study is to observe dynamically the changes in the intestinal flora, the relationship between the changes and bacterial translocation to various organs and endotoxemia. The results show that there is no obvious alteration in population of Bacteroides, but a significant increase in enteric bacilli population in the contents of the ileocecum is found. Changes in the intestinal micro-flora correlate to the positive bacterial culture of the blood, viscera, and the level of endotoxin in the plasma. The results of our work suggest that ecological imbalance in the intestinal flora may promote-the gut-derived septic process and the development of MSOF.
