Effects of Cydosponne A on Qucose Metabolism and Beta-Cell Functions in Rats
- VernacularTitle:环孢素对大鼠葡萄糖代谢及?细胞功能的作用
- Author:
Mingjun GU
;
Benli ZHANG
;
Chaoyang YE
;
Yimin LIU
;
Xiujiang YANG
- Publication Type:Journal Article
- Keywords:
immunosuppressive agent;
cyclosponne A;
glucose metabolism;
beta-cell function
- From:
Academic Journal of Second Military Medical University
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of cyclosporine A (CsA) on glucose metabolism and betancell functions in vivo in rats were investigated. CsA (20mg/kg, 2/d) was given to Spraguer-Dawley rats for 14d. After a 1.5g/kg body weight glucose load by gavage the plasma glucose at 1 h and the area under curve (AUC) of plasma glucose were higher in the CsA-treated group than in the control (P
