EFFECT OF VITAMIN A ON THE LUNG METASTASIS IN C_(57)BL MOUSE MELANOMA
- VernacularTitle:维生素A对C_(57)BL小鼠黑色素瘤肺转移的影响及其机理研究
- Author:
Jie CHENG
;
Liren YAO
- Publication Type:Journal Article
- Keywords:
Vitamin A;
Alveolar Macrophage;
Tumor metastasis
- From:
Chinese Pharmacological Bulletin
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Effects of vitamin A on antimetastatic activity of alveolar M 0 were studied. The results were as follows:1 . SD rats recieved vitamin A were killed and their alveolar M0 were harvested by lavage and cocultured with prelabelled B16 Melanoma cells for 48h in proportion of 20 : 1 , the average precentage of cytotoxity were 34.28%;2 . Zymosan-C3b rosette formation in SD rats treated with vitamin A was significantly increased. The average rosette forming rate was 43.00%. It was markdly higher than those of controls ( P
