DETECTION OF ANTIBODY RESPONSE IN INDIVIDUALS INFECTED WITH SCHISTOSOMA JAPONICUM BY DIRECT DOT-ELISA WITH-A MONOCLONAL ANTI-IDIOTYPIC ANTIBODY NP_(30)
- VernacularTitle:酶标记抗独特型抗体NP30的Dot-ELISA检测血吸虫抗体
- Author:
Ruhua TAO
- Publication Type:Journal Article
- From:
Chinese Journal of Schistosomiasis Control
1989;0(04):-
- CountryChina
- Language:Chinese
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Abstract:
The present paper reported that a murine IgM monoclonal antibody named Np30, which was proved to be an internal image of a gut associated antigen molecule of S. japonicum in function , was labelled with HRP and used to detect the antibody response of individuals acutely and chronically infected with S. japonicum by means of Dot-ELISA, a direct detection assay. The results showed that the test employed in this study was statistically comparable in effect to conventional EL1SA for the diagnosis of schistosomiasis japonica, but much simpler in operation and easier for the field use.
