Studies on Separation and Identification of the Components as well as the Tu- mor-photobiological Activities of the Major Components of Photocarcinorin
- VernacularTitle:癌光啉成分的分离鉴定及主要成分肿瘤光生物活性的研究
- Author:
Wenhui CHEN
;
Xiangsheng YIN
;
Deyu XU
- Publication Type:Journal Article
- Keywords:
photocarcinorin;
photodynamic therapy;
photochemodiagnosis and photochemotherapy;
photosensitizing ability;
photoinactivation;
photobiological activity
- From:
Academic Journal of Second Military Medical University
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The chemical composition, separation and identification of the components as well as the tumor photobiological activities of the major components of the new tumor-photochemodiagnostic and photochemotherapeutic agent photocarcinorin (PsD-007) were represented in this paper. It has been shown by the results of HPLC analysis in combination with spectroscopic determinations that PsD-007 is composed of 7 different porphyrins: MHD, DMD, MVD, AHD, HVD, Hp and Pp. The experimental results show that MHD, DMD and MVD are the major tumor photobiologically active components of PsD-007.
