Auditory Center Affected by Chronic Noise Exposure
- VernacularTitle:慢性噪声暴露对听觉中枢的影响
- Author:
Jingping FAN
;
Shuchang LU
;
Zhengyan HU
;
Zhenfu LIANG
;
Yunjing WANG
- Publication Type:Journal Article
- Keywords:
noise;
guinea pig;
superior olive;
inferior colliculus;
transmission electron microscope
- From:
Academic Journal of Second Military Medical University
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
In order to study the effect of chronic noise exposure on auditory center, seven guinea pigs were .exposured to 105 dB A noise 8h daily for 45 d. Then the animals were killed by decapitation. The superior olive and inferior colliculus were taken immediately to make the samples of electron microscope. The mitochondria swelling, membrane rupture, cristae breaking, ballooning degeneration were found. The rough surfaced endoplasmic reticulum was swollen and expanded. The lysosome and secondary lysosome were increased. The cell interstitial edema and synaptic besicle decrease were observed. The nuclear chromatid was decreased and nucleolus was kept to the side. The laminae of neurilemma of nerve fibers were dissociated, swollen and broken. The results indicate that the ultrastructure, neural cells and fibers in the auditory center are damaged by chronic noise exposure and most of these damages are irreversible.
