DISTRIBUTION AND SIGNIFICANCE OF S-100 PROTEIN IN MALIGNANT MESOTHE-LIOMAS
- VernacularTitle:S-100蛋白在恶性间皮瘤中的分布及其意义
- Author:
Guo YU
;
Weihua LI
- Publication Type:Journal Article
- Keywords:
S-100 protein Malignant mesothelioma Adenocarcinoma
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Immunohistological methods were used to investigate the presence of s-100 protein in 16 cases of malignant mesothelioma (MM) and 20 metastatic gastrointestinal adenocarcinoma of peritoneum. Positive staining for s-100 protein was observed in 14 of 16 MM, while it was negative in all metastatic gastrointestinal adenocarcinoma of peritoneum. Since antibodies to s-100 protein are readily available as standardised commercial products, the combined immunolocalisalion of s-100 protein should prove to be an efficient routine means of differentiating MM from difficult cases of metastatic gastrointestinal adenocarcinoma of peritoneum, in both necropsy and surgical cases.
