Preparation o f Epidermal Growth Factor and Its Effects on Burn Wound Healing: An Experimental Study
- VernacularTitle:表皮生长因子的制备和促进伤口愈合的实验研究
- Author:
Junlong LIU
;
Suzhen ZHANG
;
Jialing SUN
;
Yunfeng HU
;
Wenzheng WANG
;
Shengde GE
- Publication Type:Journal Article
- Keywords:
epidermal growth factor;
purification;
wound healing;
mice
- From:
Academic Journal of Second Military Medical University
1982;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The present article reports the method of preparation of epidermal growth factor (EGF) from mouse submaxillary glands by using a two-step liquid chromatography and the efficacy of EGF in promoting animal wound healing. It was found that combined purification of crude EGF is better with Bio-gel p-10 and DEAE-DE52 ion-exchange chromatographies and purified EGF has a marked enhancement of wound healing and reduction of cicatricial contracture in animals.
