Synthesis and Antifungal Activity of Sulconazole and Its Analogues
- VernacularTitle:硫康唑类似物的合成和抗真菌活性观察
- Author:
Tingsen ZHOU
;
Jianzhong YAO
;
Zenghui XING
;
Yongfu LI
- Publication Type:Journal Article
- Keywords:
sulconazole;
synthesis;
antifungal agent
- From:
Academic Journal of Second Military Medical University
1982;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
In order to search for a more potent and less toxic antifungal agent, five novel sulconazole analogues were synthesized by changing 1-imidazolyl and p-chlorobenzyl in sulconazole structure. The results of preliminary biological tests show that analogues Ⅰ and Ⅱ possess more potent antifungal activities and wider antifungal spectra than sulconazole.
