Homogenous-fat-induced Dog Model of Respiratory Distress Syndrome
- VernacularTitle:同种脂肪所致的犬RDS模型
- Author:
Guoming WU
;
Xianjian GUO
;
Baoling MAO
- Publication Type:Journal Article
- Keywords:
fat;
respiratory distress syndrome;
complement;
free radicals;
vitamin E
- From:Journal of Third Military Medical University
1984;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Homogenous fat extract was injected through the femoral vein to induce respiratory distress syndrome in 15 dogs. It was found that the changes of blood gases, chest x-ray films, and lung pathology of the dogs were similar to those of adult respiratory distress syndrome.The pathogenesis was extensive pulmonary fat embolism with complement activation and free radicals formation. Vitamin E was consumed during antiperoxidation. It is believed that this model serves better for the study of respiratory distress syndrome.
