Effects of Prostaglandin E_1 on Plasma Lipid Peroxides Level in Patients with Severe Chronic Active Viral Hepatitis
- VernacularTitle:前列腺E_1对重型慢性活动性肝炎血浆脂质过氧化物水平的影响
- Author:
Changlun HE
;
Juzheng XIANG
;
Like WU
- Publication Type:Journal Article
- Keywords:
prostaglandin;
chronic active viral hepatitis;
lipid peroxides;
nucleotide
- From:Journal of Third Military Medical University
1984;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Thirty-four patients with severe chronic active viral hepatitis were divided into 2 groups. One group was treated with prostaglandin E_1, (PGE_1,) and supportive therapy, and the other was treated with supportive therapy only and served as the control. The effects of PGE_1, on plasma lipid peroxides (LPO) level, plasma prostacyclin (PGI_2) and thromboxane A_2 (TXA_2), plasma cyclic nucleotide and liver function were determined to investigate the mechanism of PGE1. It was found that PGE_1 could achieve the following effects.1. Reduction of plasma LPO level (P
