EFFECTS OF LEUKOCYTE FACTOR ON THE RELEASE OF SUPEROXIDE ANION ( O_2~- ) IN HUMAN GRANULOCYTES
- VernacularTitle:白细胞因子对人粒细胞超氧阴离子自由基释放的影响
- Author:
Xueqi WANG
;
Qixiu FAA
;
Rubin QI
- Publication Type:Journal Article
- Keywords:
Leukocyte factor;
Concanavalin A;
Superoxide anion (O_2~-);
Granulocyte;
Activation
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
We investigated the release of superxide anion ( O2- ) in human granulocytes stimulated by leukocyte factor ( LF ) and/or concan-avalin A ( Con A ). Some amount of O2- can be released by granulocytes, when LF or Con A was applied alone. The pretreat-ment of granulocytes with a low concentration LF1 potentiated O2-release in granulocytes stimulated by Con A, and the lag time of O2-release was reduced. The results show that the granulocytes were activated by LF. This phenomenon may be related to the curative effects of LF.
