THE EFFECTS OF GINSENOSIDES OF STEM AND LEAF(GSL)ON THE LIPID REGULATION AND LIPID PEROXIDATION IN THE CHRONIC HYPER-LIPIDEMIC RABBITS
- VernacularTitle:人参茎叶皂甙对家兔慢性高脂血症的脂质调节及抗过氧化脂质作用
- Author:
Xilong ZHENG
;
Youfang YAN
- Publication Type:Journal Article
- Keywords:
Ginsenosides of Stem and Leaf;
Lipids;
Chronic Hyperlipidemia;
Lipid peroxides;
Malondialdehyde
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Thirty two rabbits were divided into 4 groups: (1) Normal diet control group, ( 2 ) Hyperlipid diet control group, ( 3 ) Hyperlipid diet group injected with 30 mg/kg GSL, ( 4 ) Hyperlipid diet group injected with 60 mg/kg GSL, The whole expeiment took about 42 days. On 24d all hyperlipid diet were removed, and only normal diet given. At the end of this experiment all rabbits were killed by bleeding and the results showed that GSL could decrease the serum lipids GSL could increase the HDL - C in the rabbits injected with 60 mg/kg GSL. GSL could protect the walls of aortas from the damage of hyperlipid serum. The contents of lipid and MDA in the Walls of aortas were decreased. GSL had the effects of protection on the heart and liver by decreasing of Total Cholesterol and MDA. So we conclude that GSL has the effects of lipid regulation and lipid antipeoxidation on the chronic hy-perjipidemic rabits.
