EFFECT OF FISH OIL ON SERUM LIPIDS IN RATS
- VernacularTitle:鱼油调整血脂作用的研究
- Author:
Hua DING
;
Wenkai YANG
;
Xiaopeng DANG
- Publication Type:Journal Article
- Keywords:
Fish oil;
EPA;
DHA;
Blood lipid
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
An EPA and DHA enriched fish oil ( containing EPA 0.24 g/L, DHA 0.47g/L ) was administered by gastric intubation at the dose of O.2ml/100g wt for a period of one month in the hyperlipoprotein-emia rats caused by high lipid and cholesterol feeding. The administration of fish oil resulted in reduction in TG ( Triglyceride ) ; TC ( Total Cholesterol ) and VLDL-C + LDL-C levels in serum. Levels of HDL2-C and ratio of HDL2/HDL3 were elevated although there was no significant change in level of HDL-C. The study suggests that oral administration of EPA and DHA enriched fish oil might reduce the developoment of atherosclerosis.
