Effect of PNS on Macrophages of Rats with Adjuvant Arthritis Releasing NO
- VernacularTitle:三七总苷对佐剂性关节炎大鼠腹腔巨噬细胞释放一氧化氮的影响
- Author:
Rubing YAO
;
Bing HU
;
Zhiming ZHAO
- Publication Type:Journal Article
- Keywords:
panax notoginseng saponins;
adjuvant arthritis;
Nitric Oxide
- From:
Journal of Zhejiang Chinese Medical University
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To investigate the influence of panax notoginseng saponins(PNS)on production of Nitric Oxide(NO) by peritoneal macrophages of rats with adjuvant arthritis(AA).[Methods]Complete Freund's adjuvant was used to induce AA in rats.Production of NO by peritoneal macrophages of rats with adjuvant arthritis was determined by nitrate reductase.[Results]PNS 0.4mg/ml increased NO synthesis and secretion from peritoneal macrophages of AA rats in vitro after four hours(P
