Flow Cytometry Analysis of 24 Snap-frozen Tissue Specimens of Ovarian Carcinoma
- VernacularTitle:24例新鲜速冻卵巢癌组织的流式细胞分析
- Author:
Zhijun JIN
;
Zhongjlng HU
;
Yizhen WU
;
Yonglian CHEN
;
Zhijiang WU
- Publication Type:Journal Article
- Keywords:
ovarian carcinoma;
flow cytometry;
DNA ploidy level;
SPF
- From:
Academic Journal of Second Military Medical University
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Flow cytometry analysis of DNA ploidy level and S-phase fraction (SPF) was carried out in 24 snap-forzen tissue specimens of ovarian carcinoma. The relationship of DNA ploidy level and SP-F with age,clinical stage, ascites, histologic type,pathological grade,lymphocyte infiltration and psammoma bodies was analyzed.Results showed that the relationship of DNA ploidy level and SPF with ascites and pathological grade was significant. Aneuploid portion and SPF in patients with ascites or pathological grade Ⅲ or Ⅱ were higher than those in patients with no ascites or pathological grade I. The author considers that DNA ploidy level and SPF of ovarian carcinoma can serve as a relatively independent objective index which reflects tumor's biological behaviours,and will be of great auxiliary value to early diagnosis and therapy of ovarian carcinoma.
