An Experimental Study of Hydroxyapatite as Bone Graft Substitute
- VernacularTitle:羟基磷灰石作为骨移植替代物的实验研究
- Author:
Zhengdong CAI
;
Zhishan LIU
;
Jianzhang GAO
;
Ximing YANG
;
Gaoyang XIE
;
Shiming MA
- Publication Type:Journal Article
- Keywords:
hydroxyapatite;
biomaterial;
bone graft
- From:
Academic Journal of Second Military Medical University
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
In this study Na2HPO4-Ca(NO3)2 system was used to synthesize hydroxyapatite (HA). Its synthetical method was simple and low in cost. With the physical-chemical characteristic observation and the animal experimentit was proved that HA was pure, with pores ranging from 20 to 200 ?m in diameter.The chemical structure of HA was similar to that of inorganic part of bones.An investigation of the histological changes and osteogenetic effectiveness of HA implanted was conducted and the mechanism of HA osteogenetic effectiveness is discussed. The study will provide scientific basis for the clinical use of HA as bone graft substitute.
