Effects of Morphine and Electroacupuncture on Substance P Level in Spinal Cord and Their Relation to Pain Threshold in Rats
- VernacularTitle:吗啡和电针对脊髓内P物质的影响及其与痛阈的关系
- Author:
Huaizheng RUAN
;
Xicheng LI
;
Haiti LI
- Publication Type:Journal Article
- Keywords:
morphine;
electroacupuncture;
spinal cord;
substance P;
radio-immunoassay;
immunohistochemistry;
pain threshold
- From:Journal of Third Military Medical University
1984;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Immunoreactive substance P (Ir-SP) level and substance P-like activity (SP-LI)in the spinal cord were determined with radioimmunoassay and immunohistochemistry in rats after they were given an intraperitoneal injection of morphine(7.5mg/kg)or electroacupunctured(3V and 3Hz)on the "Jiaji" point. It was found that pain threshold,Ir-SP content,and SP-LI activity in the dorsal horn of the spinal cord were significantly increased in the experimental group than in the control (P
