Sheep Bone Morphogenetic Protein-induced Cartilage Development in Rat Muscle in Vitro
- VernacularTitle:羊成骨蛋白体外诱导小鼠肌肉内成骨的研究
- Author:
Guomin TANG
- Publication Type:Journal Article
- Keywords:
bone morphogenetic protein;
tissue culture;
bone inducing
- From:
Academic Journal of Second Military Medical University
1985;0(06):-
- CountryChina
- Language:Chinese
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Abstract:
Sheep bone morphogenetic protein (sBMP) was chemically extracted from sheep bone matrix. When exogenous sheep BMP was introduced into 1640 culture medium at the concentrations of 1-50 ?g/ml, new cartilage developed inside the rat muscle during a 10-day latent period. With a mean rate of 52% of chondrogenesis new cartilage tissues developed in 80% of explants in the medium containing 10 ?g/ml of sBMP. The new method established in this experiment provides a useful model of tissue culture for making a progressive researching of bone inducing.
