Significance of Determination of Serum Apolipoprotein A-Ⅰ and B in Patients with Cerebral Thrombosis
- VernacularTitle:脑血栓形成患者血清载脂蛋白A-I和B测定的临床价值
- Author:
Lianqi CUI
- Publication Type:Journal Article
- Keywords:
cerebrovascular disorders;
lipids;
cerebral embolism and thrombosis;
apolipoproteins;
rate immunonephelometric assay
- From:
Academic Journal of Second Military Medical University
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Serum apolipoprotein (Apo A-Ⅰ and Apo B) and lipid (Total cholesterol: Tch, Triglyceride: TG and HDL cholesterol: HDL-C) levels were measured in 64 patients with cerebral thrombosis and 56 healthy controls. Apo A-Ⅰ and Apo B were determined by a rate immunonephelometric assay. Apo A-Ⅰ and Apo A-Ⅰ /Apo B and LDL-C/Apo B were lower; TG and HDL/Apo A-Ⅰ were higher in patients. Stepwise discriminant analysis showed that Apo A-Ⅰ was the best discriminator. The results suggest that not only the quantitative abnormalities of lipids but also the compositional abnormalities of HDL and LDL particles are existent in cerebral thrombosis; determining the serum levels of apolipoproteins may be more useful than those of lipids.
