Histological Classification and Prognosis of Neoplastic Osteoid Tissue of Osteosarcoma
- VernacularTitle:骨肉瘤肿瘤性骨样组织的分型与预后
- Author:
Dong WANG
- Publication Type:Journal Article
- Keywords:
osteosarcoma;
neoplastic osteoid;
stereology
- From:Journal of Third Military Medical University
1988;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
A histological classification based on comprehensive morphological and stereometric observation of osteosarcoma was found that osteosarcoma might be divided into three types. Type Ⅰ (mature osteoid type) , Type Ⅱ (intermediate differentiated osteoid type ) and Type Ⅲ (immature osteoid type) . Fifty patients of the seventy were followed up for years, the longest up to twenty years. The five-year survival rate for 12 patients in Type Ⅰ is 92%; for 18 patients in Type Ⅱ and 20 patients in Type Ⅲ, none of them survived more than fiye years after operation. Statistically significant difference is found between individuals in the Type Ⅰ and Type Ⅱ, in Type Ⅰ and Type Ⅲ. The results indicate that the present pathological classification may be correlated with the prognosis. The prognosis of such Type was not correlated with site and size of the tumor, the dominating cellular component, pleomorphism, mito-tic figures and the number of giant cells.
