THF TOXICITY OF MALTOL AND ITS EFFECT ON ANTIOXIDATIVE ENZYME ACTIVITIES OF ERYTHROCYTES IN MICE
- VernacularTitle:麦芽醇对小鼠的毒性作用及对红细胞抗氧化酶类活性的影响
- Author:
Huazhen PAN
;
Fubao LIN
;
Xiaobing LIU
- Publication Type:Journal Article
- Keywords:
Red cell;
Erythrocyte;
Maltol;
Superoxide dismutase;
Catalase;
Glutathione;
Malonyldialdehyde
- From:
Chinese Pharmacological Bulletin
1986;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
According to our previous experimental results, maltol is a powerful antioxidant against autoxidation and oxidative stress of eryth-rocytes. In this report, the toxicity and antioxidative action of maltol in mice was investigated. The results indicated that maltol was not toxic in mice when fed in a dose of 50mg/kg?d-1 (body weight) for 1 month. The antioxidative enzymes ( SOD and Cat ) activities and GSH content of erythrocytes were significantly increased. In addition, the lifespan of houseflies fed with maltol was prolonged.
