Studies on Capability of Esculentoside(ES) in Inducing Lympho-kines and Its Antitumor Activities
- VernacularTitle:中国商陆皂甙诱生淋巴因子的能力及其抗肿瘤细胞效应的研究
- Author:
Zhigong XU
- Publication Type:Journal Article
- Keywords:
interferon ? (IFN-?);
interleukin-2 (IL-2);
lymphotoxin (LT);
mixed lymphokine (MLF)
- From:
Academic Journal of Second Military Medical University
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Es inducing human spleen cells in 30 cases were studied. We found that Es could not only induce IFN-? from human spleen cells, but also IL-2 and LT. The mixed lymphokines containing IFN-?(3269.6?1634.4 U/ml), IL-2 (64.8?40.8 U/ml) and LT (54.4?44.6 U/ml) were induced by ES. Our study shows that the mixed lymphokines appeared to be cytotoxic to human SMMC-7721, SPC-3, HcLa, Jutkat arid Molt-4 cells lines at all levels, but it had no cytotoxic effect to normal cells (WISH cells).
