Immunohistocheinical Localization of Copper-Zinc Superoxide Dismutase in Human Hepatocellular Carcinoma and Its Surrounding Tissues
- VernacularTitle:人肝细胞癌和癌周肝铜锌超氧物歧化酶免疫组织化学定位观察
- Author:
Xiaoju YANG
- Publication Type:Journal Article
- Keywords:
hepatocellular carcinoma;
immunohistochemistry;
protein A-gold labeling probe;
copper-zinc superoxide dismutase
- From:
Academic Journal of Second Military Medical University
1985;0(05):-
- CountryChina
- Language:Chinese
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Abstract:
By using protein A-gold labeling probe, copper-zinc superoxide dismutase (Cu-Zn SOD)in paraffin-embedded sections of 24 cases of human hepatocellular carcinoma (HCC) and its surrounding liver tissues was immunolocalizied The experimental results showed that in a good many of HCCs and its surrounding liver tissues, immunostaining of Cu-Zn SOD appeared differently positive, but in 2 cases of grade Ⅱ differentiation, massive pattern of HCC, Cu-Zn SOD immunostaining was negative. In one hepatoma was clear cell carcinoma, and in another one tumor cells followed obvious fatty degenera tioa Two problems that what was significance of Cu-Zn SOD in HCQ and a few cellular nuclei labeled for Cu-Zn SOD are disscussed.
