A Preliminary Study on Therapeutic Effect of Human IFN-? on Chronic Cervicitis
- VernacularTitle:白细胞干扰素喷雾治疗慢性宫颈炎的初步研究
- Author:
Zhongshan FAN
- Publication Type:Journal Article
- Keywords:
interferon;
cervicitis;
randomized double-blind and placebo-controlled trial
- From:
Academic Journal of Second Military Medical University
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
215 cases of chronic cervicitis were treated with low concentration interferon prepared from human umbilical cord blood by spray on the focus of the disease. A randomized double-blind and placebo-eontrolled trial was used in this study. The results obtained from the clinical study showed that the total effective rate of the treated-IFN group was 93.02% (200/215) and the markedly improved rate was 49.77% (107/215). There was very significant difference between the study group and the placebo-controlled group. It is indicated that the degree and type of chronic cervicitis is related to the therapeutic effect The erosion degree of cervix is slighter, it is easier for the treatment Chronic cervicitis is divided into three types. Among them, the simple type of chronic cervicitis is easily cured and its markedly improved rate was 67.57% (50/74). The second is particle type (51.25%, 41/80). The most difficult for treatment is papillar type (26.23%, 16/61). Moreover, the mechanism of treatment of chronic cervidtis with inteiferon is also discussed
