THE EFFECT OF TETRAMETHYLPYRAZINE ANTITHROMBIN ON AGGREGATION BETWEEN MONONUCLEARCYTES AND PLATELETS
- VernacularTitle:川芎嗪抗凝血酶诱导的单个核细胞——血小板聚集
- Author:
Anguo LI
;
Shilin HE
- Publication Type:Journal Article
- Keywords:
Tetramethylpyrazine;
Antithrombin;
Aggregation between mononuclearcytes and platelets
- From:
Chinese Pharmacological Bulletin
1986;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Thrombin-induced aggregation between mononuclearcytes and platelets was investigated and shown to be calcium dependent. Tetrame-thylpyrazine inhibited the aggregation and a dose-effect relationship was demonstrated. Tetramethylpyrazine also prevented the decrease of blood leukocyte count induced with thrombin venous injection in mice. Angelica sinensis Diels and tanshinone did not show any obvious effects on thrombin-induced aggregation between mononuclearcytes and platelets.
